产品编号：D435305
产品规格：10mg
产品价格：面议
| 标准品编号: | D435305 |
| 名称: | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile |
| 别名: | N-Desmethyl Bousutinib |
| CAS号: | 380843-81-2 |
| 分子式: | C₂₅H₂₇Cl₂N₅O₃ |
| 分子量: | 516.42 |
| 种类: | Building Blocks; Miscellaneous; |
| 应用: | Proteolysis Targeting Chimera (PROTAC) is a novel approach to modern drug development programs that utilizes small compounds to target proteins for ubiquitination and degradation by proteasome. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile is a PROTAC compound, which has the potential to target oncogenic BCR-ABL for degradation. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile has also been employed in ligand-based pharmacophore modelling to identify c-Src inhibitors. |
| 参考文献 | |
