产品编号：D434235

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	D434235
名称:	(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
别名:	(αS)-2,6-Dichloro-3-fluoro-α-methylbenzenemethanol
CAS号:	877397-65-4
分子式:	C₈H₇Cl₂FO
分子量:	209.04
种类:	Building Blocks; Miscellaneous;
应用:	(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol is an intermediate in the synthetic preparation of Crizotinib (C785000), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
参考文献	De, Koning, P.D., et al.: Org. Proc. Res. Develop., 15, 1018 (2011); Nishii, H., et al.: Bioorg. Med. Chem. Lett., 20, 1405 (2010);