产品编号：D418257

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D418257
名称:	3-Dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-N-(methyl-d3)-1-propanamine
别名:	Dibenz[b,e]oxepin 1-Propanamine Deriv.;
CAS号:	138387-16-3
分子式:	C₁₉H₁₈D₃NO
分子量:	282.39
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-Dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl-N-(methyl-d3)-1-propanamine is the deuterium analog of doxepin synthesized by the N-Doxepin carbamate wit lithium aluminum deuteride. Also, it is used as an intermediate in the synthesis of Doxepin-d3 Hydrochloride (D550002), which is labeled Doxepin (D550000), which is used clinically to treat anxiety and depression. Doxepin is an anti-depressant.
参考文献	Adamczyk, M., et al.: J. Label. Compd. Radiopharm., 33, 153-155 (1993); Ribbentrop, A., et al.: Arzneim.-Forsch., 15, 863 (1965), Hobbs, D.C., et al.: Biochem. Pharmacol., 18, 1941 (1969), Pinder, R.M., et al.: Drugs, 13, 161 (1977), Shrivastava, R.K., et al.: Clin. Ther., 7, 181 (1985)