产品编号：D312500

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	D312500
名称:	N,N’-Diacetyl-L-cystine, 90%
别名:	(Ac-Cys-OH)2; N,N’-Diacetylcystine; NSC 203780; Acetylcysteine EP Impurity C; Acetylcysteine USP Impurity C
杂质:	Acetylcysteine EP Impurity C / Acetylcysteine USP Impurity C
CAS号:	5545-17-5
分子式:	C₁₀H₁₆N₂O₆S₂
外观:	白色至Light Beige Solid
熔点:	>79°C (dec.)
分子量:	324.37
储存:	冰箱保存, Under Inert Atmosphere
溶解性:	Methanol (Slightly), Water (Slightly)
种类:	Standards; Amino Acids; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N,N’-Diacetyl-L-cystine (DiNAC) is a disulfide dimer of N-acetylcysteine with immunomodulatory properties. Its intact disulfide bridge has been shown to be important for its ability to modify contact sensitivity/delayed hypersensitivity reactions in mice.1,2 At 3 µM/kg/day, DiNAC also demonstrates anti-atherosclerotic effects, improving endothelial function in Watanabe heritable hyperlipidemic rabbits. Acetylcysteine EP Impurity C.
参考文献	Pettersson, K.,et al.:The antiatherogenic effect of DiNAC: Experimental findings supporting immunomodulation as a new treatment for atherosclerosis related diseases. Cardiovascular Drug Reviews 21, 119 (2003); WÃ¥gberg, M., et al.: N,N'-Diacetyl-L-cystine (DiNAC), the disulphide dimer of N-acetylcysteine, inhibits atherosclerosis in WHHL rabbits: Evidence for immunomodulatory agents as a new approach to prevent atherosclerosis. Journal of Pharmacology and Experimental Therapeutics 299, 76 (2001)

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