产品编号：D296998

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D296998
名称:	3-Desoxyvitamin D3
别名:	(1R,3aS,7aR,E)-7a-Methyl-4-((Z)-2-(2-methylenecyclohexylidene)ethylidene)-1-((R)-6-methylheptan-2-yl)octahydro-1H-indene
CAS号:	69662-75-5
分子式:	C₂₇H₄₄
分子量:	368.64
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-Desoxyvitamin D3 is a derivative of Vitamin D3 (V676045), the vitamin that mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. It occurs in and is isolated from fish liver oils. Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. It modulates the proliferation and differentiation of both normal and cancer cells. It also has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
参考文献	Haussler, R., et al.: J. Biol. Chem., 247, 2328 (1972); Holick, M.F., Rec. Res. Canc. Res., 164, 3 (2003); Palmer, H.G., et al.: Cancer Res., 63, 7799 (2003); Welsh, J., et al.: J. Nutr., 133, 2425S (2003)