产品编号：D293945

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D293945
名称:	Des-(1-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide) 4,5-Dehydro 3-Morpholino Apixaban
别名:	3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)pyridin-2(1H)-one
分子式:	C₂₀H₂₃N₃O₃
分子量:	353.41
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Des-(1-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide) 4,5-Dehydro 3-Morpholino Apixaban is an impurity of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation
参考文献	Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011)