产品编号：D291113

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D291113
名称:	Desfluoro Lapatinib
别名:	N-(4-(Benzyloxy)-3-chlorophenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine;
分子式:	C₂₉H₂₇ClN₄O₄S
分子量:	563.07
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Desfluoro Lapatinib is the defluorinated analogue of drug Lapatinib (L175808), which is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. Lapatinib is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.
参考文献	Konecny, G., et al.: Cancer Res., 66, 1630 (2006); Geyer, C., et al.: N. Engl. J. Med., 355, 2733 (2006);