产品编号：D290780

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D290780
名称:	N-Desmethyl Alosetron
别名:	2,3,4,5-Tetrahydro-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; 2,3,4,5-Tetrahydro-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; N-Desmethyl Lotronex; Alosetron N-Desmethyl Impurity
杂质:	Alosetron N-Desmethyl Impurity
CAS号:	122852-63-5
分子式:	C₁₆H₁₆N₄O
分子量:	280.32
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Desmethyl Alosetron is a derivative of Alosetron (A575500), serotonin 5HT3-receptor antagonist. Used in treatment of irritable bowel syndrome.
参考文献	Camilleri, M., et al.: Lancet, 355, 1035 (2000), Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2002), Lewis, D., et al.: Drug Metab. Rev., 35, 1 (2003), Tang, H., et al.: J. Pharm. Sci., 95, 1783 (2006), Gleeson, M., et al.: J. Med. Chem., 50, 101 (2007),