产品编号：D437730

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D437730
名称:	2,4-Dicyano-3-(3,4-dihydroxyphenyl)-N1,N1,N5,N5-tetraethylpentanediamide
别名:	Entacapone Vanillin Dimer Impurity;
分子式:	C₂₁H₂₈N₄O₄
分子量:	400.47
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2,4-Dicyano-3-(3,4-dihydroxyphenyl)-N1,N1,N5,N5-tetraethylpentanediamide is a dimer impurity of Entacapone Vanillin (E558500) and (V097500) respectively. Entacapone acts as a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs.
参考文献	Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),