产品编号：D437312

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D437312
名称:	4,5-Dichloro-1,3-benzenedisulfonyl Dichloride-13C6
别名:	1,2-Dichlorobenzene-3,5-disulfonyl Chloride-13C6; 1,2-Dichlorobenzene-4,6-disulfonyl Chloride-13C6; 4,5-Dichloro-m-benzenedisulfonyl Chloride-13C6;
参考CAS号:	70269-54-4
分子式:	¹³C₆H₂Cl₄O₄S₂
分子量:	349.98
种类:	Standards; Isotopic Labeled Analogues;
应用:	4,5-Dichloro-1,3-benzenedisulfonyl Dichloride-13C6 is an intermediate used in the synthesis of Diclofenamide-13C6 (D436532), which is the labeled form of Diclofenamide, a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP).
参考文献	Brzozowski, Z. et al.: Eur. J. Med. Chem., 46, 3656 (2010); Tawil, R. et al.: Ann. Neurol., 47, 46 (2000); Casey, J. et al.: J. Med. Chem., 47, 2337 (2004);