产品编号：D436897
产品规格：5mg
产品价格：面议
| 标准品编号: | D436897 |
| 名称: | 17-[[[3-[(4S)-6,8-Dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]ethoxy]ethoxy]ethyl]-8-oxo-12,15-dioxa-2,7,9-triazaheptadecanamide-d8 |
| 别名: | Tenapanor-d8 |
| 参考CAS号: | 未标记：1234423-95-0 |
| 分子式: | C₅₀H₅₈D₈Cl₄N₈O₁₀S₂ |
| 分子量: | 1153.1 |
| 种类: | Standards; Isotopic Labeled Analogues; |
| 应用: | 17-[[[3-[(4S)-6,8-Dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]ethoxy]ethoxy]ethyl]-8-oxo-12,15-dioxa-2,7,9-triazaheptadecanamide-d8 (deuterium labeled) is an inhibitor of sodium/hydrogen exchanger isoform 3 (NHE3), which is a major absorptive sodium transporter. It has therapeutic potential for lowering gastrointestinal sodium absorption and improving fluid overload-related symptoms, such as hypertension and proteinuria, in patients with CKD. |
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