产品编号：D436400

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D436400
名称:	N-(3,5-Dichloro-4-pyridinyl)-3,4-dihydroxybenzamide
CAS号:	1412448-29-3
分子式:	C₁₂H₈Cl₂N₂O₃
外观:	Yellow to Brown Solid
熔点:	162-165°C
分子量:	299.11
溶解性:	Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-(3,5-Dichloro-4-pyridinyl)-3,4-dihydroxybenzamide is an intermediate in the synthesis of Roflumilast (R639700), an selective phosphodiesterase 4(PDE4) inhibitor.
参考文献	Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001), Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001), Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002), Rabe, K.F., et al.: Lancet, 366, 563 (2005),