产品编号：D290638
产品规格：25mg
产品价格：面议
| 标准品编号: | D290638 |
| 名称: | 6-Desacetyl-6-Bromo Palbociclib |
| 别名: | 6-Bromo-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Impurity F |
| CAS号: | 851067-56-6 |
| 分子式: | C₂₂H₂₆BrN₇O |
| 分子量: | 484.39 |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | 6-Desacetyl-6-Bromo Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Also, it is derived from 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one (B682195), which is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases. |
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