产品编号：D290360

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D290360
名称:	4-Desfluoro Sitagliptin
别名:	(R)-3-Amino-4-(2,5-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one-phosphate
CAS号:	1345822-87-8
分子式:	C₁₆H₁₉F₅N₅O₅P
分子量:	487.32
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-Desfluoro Sitagliptin is a metabolite of Sitagliptin phosphate (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
参考文献	Kim, D., et al.: J. Med. Chem. 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005), Bergman, A., et al: Clin. Ther. 28, 55 (2006)