产品编号：D290255

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	D290255
名称:	Desloratadine Citric Amide
别名:	8-Chloro-6,11-dihydro-11-(1-[3,4-dicarboxy-3-hydroxy-butanamido]-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;
CAS号:	1797131-43-1
分子式:	C₂₅H₂₅ClN₂O₆
分子量:	484.93
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Desloratadine Citric Amide is an impurity of Desloratadine (D290250), an nonsedating-type histamine H1-receptor antagonist. Desloratadine is an active metabolite of Loratadine (L469575) and is known to inhibit the generation and release of inflammatory mediators from basophils and mast cells.
参考文献	Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000); Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000); Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2001);