产品编号：D290055

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D290055
名称:	Deshydroxy Sotalol Hydrochloride
别名:	N-(4-(2-(Isopropylamino)ethyl)phenyl)methanesulfonamide Hydrochloride; USP Sotalol Related Compound C
CAS号:	16974-44-0
参考CAS号:	Free Base: 16974-42-8
分子式:	C₁₂H₂₁ClN₂O₂S
外观:	白色至白色固体
熔点:	>248° C (dec.)
分子量:	292.83
储存:	冰箱保存
溶解性:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Deshydroxy Sotalol Hydrochloride is an impurity in the synthesis of Sotalol (S677300), a potent α-adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period.
参考文献	Uloth, et al.: J. Med. Chem., 9, 88 (1966), Groh, W.J., et al.: Chirality, 5, 8 (1993), Pasnani, J.S., et al.: J. Pharmacol. Exp. Ther., 271, 184 (1994),