产品编号：D289695

产品规格：100mg

产品价格：面议

---

产品详情

标准品编号:	D289695
名称:	3-Descyano 3-Bromo-febuxostat
别名:	2-[3-Bromo-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid; 2-(3-Bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic Acid
CAS号:	144060-40-2
分子式:	C₁₅H₁₆BrNO₃S
分子量:	370.26
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-Descyano 3-Bromo-febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
参考文献	Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)