产品编号：D289258

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D289258
名称:	Desethyl Azilsartan Medoxomil
别名:	3-[[2'-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-2,3-dihydro-2-oxo-1H-benzimidazole-4-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
CAS号:	1417576-00-1
分子式:	C₂₈H₂₀N₄O₈
分子量:	540.48
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Desethyl Azilsartan Medoxomil is an impurity from the synthesis of Azilsartan Medoxomil (A926910). Azilsartan medoxomil is a long-acting angiotensin II receptor blocker (ARB) that is used to lower hypertension. When Azilsartan medoxomil enters the gastrointestinal tract, it is rapidly converted to its active form, Azilsartan (A926900).
参考文献	Radl, S., et al.: Org. Process. Res. Dev., 17),Â77-86 (2013); Baker, W. & White, W.: Pharmacotherapy, 45, 1506 (2011); Cushman, W., et al.: Hypertension, 60, 310 (2012); Lastra, G., et al.: Cardio. Med. 3, 154 (2013); Miura, S., et al.: Hypertens. Res., 36, 134 (2012); Rakugi, H., et al.: Hypertens. Res., 35, 552 (2012)