Desethyl Sacubitril-d4

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产品编号:D288248

产品规格:5mg

产品价格:面议


产品详情

标准品编号: D288248
名称: Desethyl Sacubitril-d4
别名: (αR,γS)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl[1,1'-biphenyl]-4-pentanoic Acid-d4; (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic Acid-d4; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid-d4; LBQ 657-d4; Sacubitrilat-d4; [S-(R*,S*)]-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid-d4
参考CAS号: 类似: 149709-44-4
分子式: C₂₂H₂₁D₄NO₅
外观: 白色固体
熔点: 158-164°C
分子量: 387.46
储存: 冰箱保存
溶解性: DMSO (Slightly), Methanol (Slightly)
种类: Standards; Isotopic Labeled Analogues;
应用: Desethyl Sacubitril-d4 is the labelled, deuterated version of Desethyl Sacubitril which is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
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