产品编号：D288238

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D288238
名称:	2-Desaminosulfonyl 3-Aminosulfonyl N-Acetyl Dorzolamide
别名:	N-Ethyl-N-((4S,6S)-6-methyl-7,7-dioxido-3-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetamide
分子式:	C₁₂H₁₈N₂O₅S₃
外观:	白色固体
分子量:	366.48
溶解性:	Dichloromethane, Methanol
种类:	Standards; Miscellaneous;
应用:	2-Desaminosulfonyl 3-Aminosulfonyl N-Acetyl Dorzolamide is an intermediate in the synthesis of 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide (D288235), which is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100).
参考文献	Blacklock, T., et al.: J. Org. Chem., 58, 1672 (1993); Tempkin, O., et al.: Tetrahedron: Asym., 7, 2721 (1996)