产品编号：D282025

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D282025
名称:	O-Desbromo-pyrimidinyl Macitentan
别名:	N-[5-(4-Bromophenyl)-6-[2-hydroxyethoxy]-4-pyrimidinyl]-N'-propylsulfamide
CAS号:	1393813-43-8
分子式:	C₁₅H₁₉BrN₄O₄S
外观:	白色固体
熔点:	130-132ºC
分子量:	431.3
储存:	冰箱保存
溶解性:	Chloroform (Slightly), Methanol (Slightly, Heated)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	O-Desbromo-pyrimidinyl Macitentan is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension.
参考文献	Emoto, N. Ensho to Men'eki, 20, 487 (2012); Bruderer, S., et al.: Xenobiotica, 42, 901 (2012); Bolli, M.H., et al.: J. Med. Chem., 55, 7849 (2012)