产品编号：D281980

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D281980
名称:	3-Desamino-3,4-dehydro Sitagliptin
别名:	(E)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-3-en-1-one
杂质:	Sitagliptin Tablets EP Impurity FP-C
CAS号:	1803026-58-5
分子式:	C₁₆H₁₂F₆N₄O
外观:	白色至白色固体
熔点:	113-115°C
分子量:	390.28
储存:	-20°C Freezer, Under inert atmosphere
溶解性:	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-Desamino-3,4-dehydro Sitagliptin is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
参考文献	Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005); Bergman, A., et al: Clin. Ther. 28, 55 (2006)

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