产品编号：D235370

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D235370
名称:	(2'R)​-2'-​Deoxy-​2'-​fluoro-​2'-​methyl-uridine 5'-​Triphosphate Triethylammonium Salt
别名:	Sofosbuvir Impurity; RO 2433 Triphosphate Triethylammonium Salt
参考CAS号:	1015073-42-3 free acid; 1621884-22-7 Na salt
分子式:	C₂₈H₆₁FN₅O₁₄P₃
外观:	白色至白色固体
熔点:	56 - 60°C
分子量:	803.73
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解性:	Methanol (Slightly), Water (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2'R)​-2'-​Deoxy-​2'-​fluoro-​2'-​methyl-uridine 5'-​Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate.
参考文献	Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010);