产品编号：D232855

产品规格：2g

产品价格：面议

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产品详情

标准品编号:	D232855
名称:	rac-2-Deoxy-D-erythro-pentofuranose 3,5-Di-p-toluate(Decitabine Impurity)
别名:	p-Toluic Acid 3,5-Diester with 2-Deoxy-D-erythro-pentofuranose
CAS号:	17117-72-5
分子式:	C₂₁H₂₂O₆
分子量:	370.4
种类:	Research Tools;
应用:	2-Deoxy-D-erythro-pentofuranose 3,5-di-p-toluate is an impurity of Decitabine (α-isomer: D226730), a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, “normalizing” gene expression in cancerous cells.
参考文献	Aribi, A., et al.: Cancer, 109, 713 (2007); Issa, J., et al.: Blood, 103, 1635 (2004); Kantarjian , H., et al.: Cancer, 98, 522 (2003); Momparler, R., et al.: Anti-Cancer Drug., 8, 358 (1997); Plimack, E., et al.: Leukemia Lymphoma, 48, 1472 (2007)