产品编号：D232060

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	D232060
名称:	3-Deoxy-3-acetylabiraterone-3-ene
别名:	1-((8R,9S,10R,13S,14S)-10,13-Dimethyl-17-(pyridin-3-yl)-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl)ethanone
分子式:	C₂₆H₃₁NO
外观:	白色至淡黄色固体
熔点:	>120°C (dec.)
分子量:	373.53
储存:	-20°C Freezer, Under inert atmosphere
溶解性:	Chloroform (Slightly), Methanol (Slightly, Heated)
种类:	Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-Deoxy-3-acetylabiraterone-3-ene is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
参考文献	Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)