产品编号：D230352

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D230352
名称:	5-Dehydro Tolvaptan-d7
别名:	N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide-d7; 1H-1-Benzazepine, Benzamide Deriv.-d7; 7-Chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-5-Oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-d7
CAS号:	1296212-29-7
参考CAS号:	137973-76-3
分子式:	C₂₆H₁₆D₇ClN₂O₃
外观:	Off-white Solid
分子量:	453.97
种类:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	5-Dehydro Tolvaptan-d7 is an intermediate in synthesizing Tolvaptan-d7 (T536652), a labelled Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
参考文献	Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006)