产品编号：D230230

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D230230
名称:	De-α-D-glucopyranoside Hydroxy Canagliflozin
别名:	3-((5-(4-Fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl
分子式:	C₁₈H₁₅FOS
分子量:	298.37
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	De-α-D-glucopyranoside Hydroxy Canagliflozin is an impurity in the synthesis of the drug Canagliflozin (C175190). Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
参考文献	Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);