产品编号：D228735

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D228735
名称:	Defluoro-Canagliflozin
别名:	(1S)-1,​5-​Anhydro-​1-​C-​[4-​methyl-​3-​[(5-​phenyl-​2-​thienyl)​methyl]​phenyl]​-D-​glucitol, ​,
CAS号:	842133-16-8
分子式:	C₂₄H₂₆O₅S
分子量:	426.53
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Defluoro-Canagliflozin is an impurity of Canagliflozin (C175190), a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
参考文献	Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);