产品编号：D198920

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D198920
名称:	(S)-N-Deacetyl Colchicine
别名:	(7S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxy-benzo[a]heptalen-9(5H)-one; (-)-7-Deacetylcolchicine; NSC 201400;
CAS号:	3476-50-4
分子式:	C₂₀H₂₃NO₅
外观:	Light Yellow to Dark Yellow Solid
熔点:	80 - 85°C
分子量:	357.4
储存:	-20°C Freezer, Under Inert Atmosphere
溶解性:	Chloroform (Slightly), DMSO, Methanol (Slightly)
种类:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
危险品:	Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献	Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998), Alali, F., et al.: Phytochem. Anal., 19, 385 (2008), Chang, D., et al.: Bioorg. Med. Chem. Lett., 19, 4416 (2009),

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