产品编号：D198900

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	D198900
名称:	N-Deacetyl Colchiceine
别名:	(7S)-7-Amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-benzo[a]heptalen-9(5H)-one; NSC 36796; Trimethylcolchicinic Acid;
CAS号:	3482-37-9
分子式:	C₁₉H₂₁NO₅
外观:	Pale Yellow to Light Green Solid
熔点:	156-161˚C
分子量:	343.37
储存:	-20ËšC Freezer
溶解性:	Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
参考文献	Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998), Tanaka, H., et al.: Canc. Res., 69, 6978 (2009), D'Elia, M., et al.: Chem. Biol., 16, 548 (2009),

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