Darinaparsin-d3

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产品编号:D193428

产品规格:10mg

产品价格:面议


产品详情

标准品编号: D193428
名称: Darinaparsin-d3
别名: N-[S-(Dimethylarsino)-N-L-γ-glutamyl-L-cysteinyl]-glycine-d5; Dimethylarsinic Glutathione-d5; ZIO 101-d5; Zinapar-d5; L-γ-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine-d5
参考CAS号: 未标记:69819-86-9
分子式: C₁₂H₁₉D₃AsN₃O₆S
分子量: 414.32
种类: Building Blocks; Isotopic Labeled Analogues;
应用: Darinaparsin-d3 is the isotope labelled analog of Darinaparsin. Darinaparsin is an arsenic cytotoxin that has been used in pharmacological activities to evaluate the effect on survival an radiosensitivity of tumor cells in vitro under normoxia and hypoxia and in vivo using xenograft models. Darinaparsin has significant and preferential cytotoxic and radiosensitizing effects on solid tumors as compared with normal cells. Darinaparsin may therefore increase the therapeutic index of radiation therapy and has near term translational potential.
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