产品编号：D157240

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	D157240
名称:	(1R,​2R,​3S,​5S)​- 3-​(3,​4-​Dichlorophenyl)​-​8-​methyl-8-​azabicyclo[3.2.1]​octane-​2-​carboxylic Acid Methyl Ester
别名:	[1R-(2-endo,3-exo)]-3-(3,4-Dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester
CAS号:	157239-71-9
分子式:	C₁₆H₁₉Cl₂NO₂
分子量:	328.23
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(1R,​2R,​3S,​5S)​- 3-​(3,​4-​Dichlorophenyl)​-​8-​methyl-8-​azabicyclo[3.2.1]​octane-​2-​carboxylic Acid Methyl Ester is an intermediate in the synthesis of Tesofensine (T136500), which is a serotonin–noradrenaline–dopamine reuptake inhibitor from the phenyltropane family of drugs, which is currently in clinical development for the treatment of obesity.
参考文献	Hansen, H., et al.: Pharmacology, Biochemistry and Behavior, 110, 265 (2013);