产品编号：D100085
产品规格：10mg
产品价格：面议
| 标准品编号: | D100085 |
| 名称: | Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt (80%) |
| 别名: | N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine β-D-Glucopyranuronosyl Ester Trifluoroacetic Acid Salt; |
| 参考CAS号: | Free Base:1015167-40-4 |
| 分子式: | C₃₁H₃₃N₇O₉ •xC₂HF₃O₂ |
| 外观: | 灰白色至浅褐色固体 |
| 熔点: | >155°C (dec.) |
| 分子量: | 647.6411402 |
| 储存: | Hygroscopic, -20ËšC Freezer, Under Inert Atmosphere |
| 溶解性: | DMSO (Slightly), Methanol (Slightly, Heated) |
| 稳定性: | Unstable in solution |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt is a major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys. NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers). |
| 参考文献 | |
