产品编号：C990340

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	C990340
名称:	(2S,3R,4R,5S)-6-((2-((2-((4-Cyanophenyl)amino)pyrimidin-4-yl)amino)-5-((E)-2-cyanovinyl)-3-(hydroxymethyl)benzyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid
参考CAS号:	Parent compound: 500287-72-9
分子式:	C₂₈H₂₆N₆O₈
分子量:	574.54
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2S,3R,4R,5S)-6-((2-((2-((4-Cyanophenyl)amino)pyrimidin-4-yl)amino)-5-((E)-2-cyanovinyl)-3-(hydroxymethyl)benzyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid is a metabolite of Rilpivirine (R509800), which is a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine is an anti-HIV agent that seems to be well tolerated with less CNS disturbance than Efavirenz and has non-teratogenic potential.
参考文献	Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001)