产品编号：C990035

产品规格：5mg

产品价格：面议

---

产品详情

标准品编号:	C990035
名称:	2-[[4-(1-Naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid
CAS号:	1038366-57-2
分子式:	C₁₄H₁₁N₃O₂S
分子量:	285.32
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-[[4-(1-Naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.
参考文献	Burns, C., et al.: Lancet 377, 165 (2011); Miner, J. et al.: PCT Int. Appl. WOÂ2011159732ÂA1Â20111222 (2011);ÂCrittenden, D. B. et al.: Clinical InvestigationÂ1,Â1563-1575 (2011)