产品编号：C984870

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	C984870
名称:	trans-N-(2-Chloroethyl)-N'-(4-hydroxycyclohexyl)urea
别名:	N-(2-Chloroethyl)-N'-(trans-4-hydroxycyclohexyl)urea;
CAS号:	56239-23-7
分子式:	C₉H₁₇ClN₂O₂
外观:	白色固体
分子量:	220.7
溶解度:	Methanol;
类别:	Building Blocks; Miscellaneous;
应用:	trans-N-(2-Chloroethyl)-N'-(4-hydroxycyclohexyl)urea is an intermediate used in the synthesis of trans-4-Hydroxy-lomustine (H942995), which is an impurity of lomustine (L469440) which is a chloroethylnitrosourea derivative with antitumor activity. Lomustine is similar to carmustine, chlorozotocin, nimustine, and ranimustine.
参考文献	Johnston, T.P., et al.: J. Med. Chem., 9, 892 (1966); Oliverio, V.T., et al.: Cancer Res., 30, 1330 (1970); Thompson, G.R., et al.: Toxicol. Appl. Pharmacol., 21, 405 (1972); Al-Shammary, F.J., et al.: Anal. Profiles Drug Subs., 19, 315 (1990)