产品编号：C955990

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	C955990
名称:	(3S,5S)-6-Cyano-3,5-dihydroxyhexanoic Acid 1,1-Dimethylethyl Ester
CAS号:	1105067-92-2
分子式:	C₁₁H₁₉NO₄
分子量:	229.27
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(3S,5S)-6-Cyano-3,5-dihydroxyhexanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of (3S,5S)-Atorvastatin Sodium Salt (A791735), which is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
参考文献	Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18. 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)