产品编号：C781795
产品规格：5mg
产品价格：面议
| 标准品编号: | C781795 |
| 名称: | Crenolanib |
| 别名: | 1-[2-[5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine; ARO 002; CP 868596; [1-[2-[5-(3-Methyloxetan-3-ylmethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-yl]amine |
| CAS号: | 670220-88-9 |
| 分子式: | C₂₆H₂₉N₅O₂ |
| 分子量: | 443.54 |
| 类别: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | Crenolanib (CP-868569) is a tyrosine kinase inhibitor that acts by specifically inhibiting the receptor tyrosine kinases PDGFRα and PDGFRβ. Crenolanib (CP-868569) inhibits the activity of PDGFRα D842V kinase and prevented the phosphorylation of wild type PDGFRα. Crenolanib (CP-868569) possesses potential antineoplastic activity. Crenolanib is believed to suppress PDGFR-related signal transduction pathways leading to the inhibition of tumor angiogenesis and tumor cell proliferation. |
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