Combretastatin A4 Phosphate Disodium Salt

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产品编号:C643025

产品规格:5mg

产品价格:面议


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标准品编号: C643025
名称: Combretastatin A4 Phosphate Disodium Salt
别名: 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol 1-(Dihydrogen phosphate) Sodium Salt; CA 4P;
CAS号: 168555-66-6
参考CAS: Free Acid: 222030-63-9
分子式: C₁₈H₁₉Na₂O₈P
外观: 白色至白色固体
熔点: >187°C (dec.)
分子量: 440.29
储存: 冰箱保存
溶解度: Methanol (Slightly), Water (Slightly)
类别: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Phosphorylated Combretastatin, a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site.
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