产品编号：C633155

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	C633155
名称:	Cobicistat Open Morpholine
别名:	Thiazol-5-ylmethyl ((2R,5R)-5-((S)-4-(N-(2-Hydroxyethyl)formamido)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)butanamido)-1,6-diphenylhexan-2-yl)carbamate;
分子式:	C₃₉H₅₁N₇O₆S₂
分子量:	778
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
应用:	Cobicistat Open Morpholine is an impurity of Cobicistat (O849600), an HIV protease inhibitor and has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer, significantly increasing their plasma concentrations.
参考文献	Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012);