产品编号：C609788

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	C609788
名称:	4-(2-Chlorophenyl)-2-methyl-5-oxo-4,4a,5,7,8,10-hexahydro-1H-pyrido[2',3':2,3]azeto[2,1-c][1,4]oxazine-3-carboxylic Acid
分子式:	C₁₇H₁₇ClN₂O₄
外观:	Off-white Solid
分子量:	348.78
储存:	-20°C Freezer
溶解度:	Chloroform; Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-(2-Chlorophenyl)-2-methyl-5-oxo-4,4a,5,7,8,10-hexahydro-1H-pyrido[2',3':2,3]azeto[2,1-c][1,4]oxazine-3-carboxylic Acid is an intermediate in the synthesis of 3-O-Desethyl-5-O-desmethyl Amlodipine (D291305). 3-O-Desethyl-5-O-desmethyl Amlodipine is an impurity of Amlodipine (A633495), which is a dihydropyridine calcium channel blocker.
参考文献	Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995)