产品编号：C596195

产品规格：50mg

产品价格：面议

---

产品详情

标准品编号:	C596195
名称:	1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea
别名:	N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea
CAS号:	1129683-83-5
分子式:	C₁₄H₁₀ClF₃N₂O₂
外观:	白色至淡黄色固体
熔点:	204-206°C
分子量:	330.69
储存:	冰箱保存
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is an impurity of Sorafenib (S676850), a kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis.
参考文献	Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003), Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004), Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004), Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006),