产品编号:C587843
产品规格:100mg
产品价格:面议
| 标准品编号: | C587843 |
| 名称: | (6R,7R)-3-(Chloromethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester |
| 别名: | (6R-trans)--3-(Chloromethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester; (6R,7R)-4-Methoxybenzyl 3-(Chloromethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| CAS号: | 101182-25-6 |
| 分子式: | C₂₂H₂₁ClN₂O₅S₂ |
| 外观: | Off 白色固体 |
| 分子量: | 493 |
| 溶解度: | Dichloromethane |
| 类别: | Standards; Miscellaneous; |
| 应用: | (6R,7R)-3-(Chloromethyl)-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester is an intermediate in synthesizing Nitrocefin (N493815), a chromogenic β-lactamase substrate that undergoes colour change from yellow to red as the amide bond in the β-Lactam ring is hydrolyzed by β-lactamase. Nitrocefin undergoes colour changes induced by lactamases produced by Gram-positive and Gram-negative bacteria. Several studies have utilized the colour changing properties of Nitrocefin for the detection of β-lactamase activity from bacterial cell extracts by isoelectric focusing and spectroscopy. Nitrocefin has also been used in studies involving β-lactamase resista |
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