产品编号：C587785

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	C587785
名称:	N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide
别名:	PS 1145
CAS号:	431898-65-6
分子式:	C₁₇H₁₁ClN₄O
分子量:	322.75
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide is an inhibitor of IKKβ, an enzyme involved with the cytokine-activated intracellular signaling pathway that regulates the immune response. N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide also inhibits osteoclast differentiation.
参考文献	Li, Y. and Prakash, S. R.: J. Labelled Comp. 48, 323 (2005); Lupino, E., et al.: J. Immunol. 188, 2545 (2012) von Metzler, I., et al.: Leukemia 21, 2025 (2007)