产品编号：C441120

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	C441120
名称:	(R,R)-Cilastatin
别名:	(Z)-7-(((R)-2-Amino-2-carboxyethyl)thio)-2-((R)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoic Acid
CAS号:	107872-23-1
分子式:	C₁₆H₂₆N₂O₅S
外观:	白色至白色固体
熔点:	180-185°C
分子量:	358.45
储存:	冰箱保存, under inert atmosphere
溶解度:	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(R,R)-Cilastatin is a derivative of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
参考文献	Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),