产品编号：C422245

产品规格：2.5g

产品价格：面议

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产品详情

标准品编号:	C422245
名称:	4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate
别名:	N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[[(4-Chloro-3-(trifluoromethyl)phenylamino)carbonyl]oxy]-2-fluorophenyl]-Urea
分子式:	C₂₂H₁₂Cl₂F₇N₃O₃
分子量:	570.24
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate is an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
参考文献	Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)