产品编号：C422225

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C422225
名称:	1-(4-Chloro-3-(trifluoromethyl)phenyl)urea
别名:	Sorafenib Impurity 1
分子式:	C₈H₆ClF₃N₂O
分子量:	238.59
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-(4-Chloro-3-(trifluoromethyl)phenyl)urea is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.
参考文献	Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)