产品编号：C382100

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C382100
名称:	Chloro Sofosbuvir Desphosphate
别名:	(2'R)-2'-Chloro-2'-deoxy-2'-methyl-uridine
CAS号:	1496551-72-4
分子式:	C₁₀H₁₃ClN₂O₅
分子量:	276.67
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
应用:	Chloro Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.
参考文献	Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)