产品编号：C380745

产品规格：25mg

产品价格：面议

---

产品详情

标准品编号:	C380745
名称:	N-(5-Chloropyridin-2-yl)-N'-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide
别名:	Edoxaban Impurity H; 2,4-diepi-Edoxaban; (2S,4R)-Edoxaban;
CAS号:	1255529-28-2
分子式:	C₂₄H₃₀ClN₇O₄S
分子量:	548.06
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-(5-Chloropyridin-2-yl)-N'-[(1S,2S,4R)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide or Edoxaban Impurity H is an impurity of Edoxaban (E555520) which is an anticoagulant drug which acts as a direct factor Xa inhibitor. Edoxaban Impurity H serves as a useful pharmaceutical standard.
参考文献	Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010); Yoshino, T., et al.: Preparation of stereoisomers of N1-(5-chloropyridin-2-yl)-N2-[(1S, 2R, 4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide as pharmaceutical standards and as drugs for treating thrombosis, US Patent 20120053349, Mar 1, 2012;