产品编号：C380615

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	C380615
名称:	6-Chloropyridine-2-carboxylic Acid
别名:	6-Chloropicolinic Acid; 6-Chloro-2-pyridinecarboxylic Acid; 2-Chloropyridine-6-carboxylic Acid; NSC 51587
CAS号:	4684-94-0
分子式:	C₆H₄ClNO₂
外观:	白色至淡黄色固体
熔点:	185-189°C
分子量:	157.55
储存:	-20°C Freezer
溶解度:	DMSO (Slightly), Methanol
类别:	Building Blocks; Miscellaneous;
应用:	6-Chloropyridine-2-carboxylic Acid is an intermediate of Sorafenib b(S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
参考文献	Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)